The Manchester United loanee is set to deputise for the absent Marco Reus, who is expected to miss out with a toe injury.
Januzaj moved to Dortmund on loan towards the end of the transfer window and made a storming start to life in Germany, with a goal on his debut against St Pauli in a friendly.
And Tuchel praised the Belgian's impact, while revealing he will consider him from the start tomorrow.
"Our first impression of Adnan is good," he said.
"He's a very exciting, creative player but it will still take time for him to get used to us, to the defensive work and the training intensity too."
GETTY
Adnan Januzaj is set to make his Bundesliga debut this weekend
Reus is expected to return to action soon after missing Germany's Euro 2016 qualifiers in the international break.
The German, 26, has been heavily linked with a move away from the club, with United and rivals Liverpool thought to be tracking his progress.
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Spanish giants Barcelona and Real Madrid are also understood to be huge admirers.
However, Tuchel, whose side are top of the league with three wins from three this season, is more concerned with matters on the pitch, and has urged his players to pick up where they left before going to play for their countries.
"We want to continue to be at the top. We need to look at each game from week to week," he added.
"A comparison with Bayern isn't forbidden but I don't care if we're on the same level as them."