Hopes are high for the England side after an impressive performance in the group stages, despite losing to Belgium last week.
The team ended the game injury-free, so hopes are the Three Lions will maintain the momentum that accumulated with Harry Kane’s hat-trick in the 6-1 triumph over Panama.
Colombia, whose victory over Senegal was marred by star playmaker Jamie Rodriguez suffering a calf injury,arestill waiting to see if he’ll be fit to play.
Manager Jose Pekerman said he was "very worried" about his star midfielder.
What are the latest odds?
According to the latest Ladbrokes odds, Englandarefavoured to win tonight - giving hopeful fans a boost that football may well be coming home.
Englandare23/20 to win today while the latest odds on Colombia securing a win are 29/10.
World Cup England v Colombia: Harry Kane is favoured 3/1 to score first in Spartak Stadium in Moscow (Image: Getty )
And Tottenham Hotspur striker and England captain Harry Kaneisfavoured 3/1 to score first in Spartak Stadium in Moscow tonight.
England coach Gareth Southgate has called on the players to grasp this golden opportunity with both hands to help bring the World Cup trophy home.
After years of disconnect with the public, the Three Lions have ignited interest in the national team for the first time in years.
Southgate is confident the defeat to Belgium hasn’t thrown the team off their path to glory too much.
World Cup England v Colombia: Colombia's injured Jamie Rodriguez (Image: Getty )
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Speaking from Spartak Stadium, he said: "I think life is always about opportunity presenting itself and taking control of it, taking charge of it.
"We said we didn't want this tournament to take hold of us and push us around. We wanted to attack it and make sure we were in charge of our destiny.
"Of course, once you get to these games there are really fine margins, so there are games that you know as a team if you want to progress to have success, you have to win these matches.
"All our preparations around that we feel we are in a good place. Now we have to stop talking and go and deliver."
World Cup England v Colombia: Gareth Southgate has called on the players to grasp this opportunity (Image: Getty )